Case of the Month #27 - rhabdomyolysis

Published 02/03/2022

Tenets of Treatment

  • Management of the underlying precipitant such as cessation of statins, release of compartment pressure, treatment of infection etc.
  • Early identification and crystalloid fluid resuscitation (ideally within <6 hours as this is associated with a reduction in incidence of AKI).
  • Consensus guidelines suggest maintaining urine output of 200-300ml/hr or 3mls/kg/hr until CK normalises4.
  • Renal replacement therapy – commonest indications are metabolic acidosis and hyperkalaemia resistant to medical management.