Key Take Home Messages
- Cardiac biomarkers and echocardiography can be useful in prognosticating risk for mortality in patients with acute PE.
- Acute massive PE can lead to RV pressure and volume overload, RV dysfunction, and cardiogenic shock.
- Acute RV failure is the leading cause of death in patients with massive PE.
- Systemic thrombolysis is currently indicated for massive PE, but is not without significant risk of major haemorrhage.